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Sorsby Fundus Dystrophy

A Rare Inherited Retinal Disease — Early Diagnosis and Treatment is Critical

What is Sorsby Fundus Dystrophy?

Sorsby Fundus Dystrophy (SFD) is a rare, inherited retinal disease that can cause rapid and significant vision loss. It is distinguished by its aggressive course — vision can deteriorate quickly, particularly due to the development of abnormal blood vessel growth beneath the retina.

Cause

Caused by mutations in the TIMP3 gene, which encodes a protein involved in regulating tissue remodeling in the eye. Mutations lead to abnormal deposits and vulnerability to choroidal neovascularization (CNV) — the growth of abnormal blood vessels that can leak and scar retinal tissue.

Symptoms

Why Early Diagnosis Matters

Sorsby Fundus Dystrophy can progress significantly faster than other inherited macular dystrophies. Complications such as choroidal neovascularization can cause irreversible vision loss if not detected and addressed promptly.

Treatment at Our Center

Our center offers Stem Cell Therapy as part of a comprehensive management approach. The goal is to support remaining retinal tissue, reduce inflammatory processes, and slow the progression of degeneration. Early consultation is strongly recommended.

Related Conditions

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